-Butyrolactone (GBL) is a colorless, hygroscopic fluid with a mild odor that can be mixed with water. The simplest is a 4-carbon lactone. GBL functions as a recreational CNS depressant with effects resembling those of barbiturates in humans and functions as a prodrug for -hydroxybutyric acid (GHB). It is produced as an intermediate in the synthesis of other compounds, such as methyl-2-pyrrolidone.
How is GBL produced?
GBL extracts were discovered in samples of pure wine. This discovery demonstrates that GBL is naturally present in some wines and is also present in similar goods. The GC/MS analysis with a straightforward removal procedure was simply performed after the detection concentration of approximately 5 g/mL. GBL can be discovered in cheese tastes, however overall, the finished dish contains only 0.0002% GBL.
Industrial production of -Butyrolactone involves dehydrogenation of 1,4-butanediol at 180–300 °C, atmospheric pressure, and the presence of a copper catalyst.
This technique has a 95% success rate. By removing the liquid gas phase, cleaning is accomplished.
In the lab, tetrahydrofuran can also be oxidized using substances such as aqueous sodium bromate. The Sandmeyer reaction is a different pathway that GABA employs.
GBL uses include
There are numerous industrial applications for GBL. Pyrolidones, which are frequently employed in industrial chemicals as an intermediary in manufacture, are one significant application of GBL. Due to its strong solvency qualities, GBL is also employed as a second important ingredient in solutions like electronic circuit board cleaners, paint strippers, and nail polish removers. For the cellulose acetate, polystyrene, and polyacrylonitrile solvents. Herbicide and pharmaceutical manufacture is also a part of synthesis; examples include the production of DL-methionine, piperidine, phenylbutyric acid, and thiobutyric acid.
GBL is misused as a liquid that is frequently misrepresented as GHB when being sold illegally. A 2.5 g of GHB 49 is roughly similar to 1 ml of high-purity GBL. GBL is sold by online chemical vendors that advertise it as a cleaning solvent, all-purpose remover, chrome polish, and wheel cleaner.